1. Complete all the LINKS to your classmates’ website in your LINKS page.
  2. In your final exam page insert or add and answer the following:
  3. What is Green Technology?
  4. What are the Goals of Green Technology?
  5. Examples of Green Technology Subject Areas
  6. Examples of Green Technologies
  7. Top Ten U.S. Cities with Most Green Technologies
  8. The Top 10 Green-Tech Breakthroughs of 2008
  9. What is a Netbook?
  10. What is IVF – In Vitro Fertilization?
  11. List down Nadya Suleman’s octuplet babies, their names, gender, birth weight in birth order.
  12. What are the services of Department of Science and Technology (DOST) in the Philippines
  13. What are the Agencies of DOST
  14. Five Sectoral Planning Councils of DOST(Brief Function and Description)
  15. Seven Research and Development institutes of DOST (Brief Function and Description)
  16. Seven Service Institutes of DOST (Brief Function and Description)
  17. Two Advisory Bodies of DOST (Brief Function and Description)
  18. Who is the Secretary of the Department of Science and Technology?
  19. EDIT your SITE. Your site must look PROFESSIONALLY.
  20. FINALLY add these links in your LINKS page

Green Technology Goals

Should policy aim at specific goals or at enabling mechanisms to reach those goals?

I ask because American energy efficiency improves on average by 2% per year. In the past, we have sort of squandered that efficiency by asking motors to carry a greater load and by getting newer and bigger appliances.

If, on the other hand, we simply used these efficiency gains to reduce energy consumption, by 2050 we would be using half the energy we're using today. That's all we would have to do.

Now, if we also started reducing the load on motors, turbines, etc., by driving cars that weighed less and plugging gaps in our homes, we might be able to do it quicker.

And that's where policy should point--we know that new technology is just around the corner, but we don't know which technology will best serve our needs or when it will be of optimum efficiency to adopt it. So why not focus our energy on a proven way of getting to where we want to be? Just asking...

 

director George Elvin interviewed by Progressive Investor

Thursday, December 13th, 2007

stockticker.jpgRona Fried, PhD, publisher, interviewed Green Technology Forum director Dr. George Elvin for the November 2007 issue of Progressive Investor:

Nanotechnology & Green Building

When you think of nanotechnology do you think of green building? Probably not, but nanotech, the manipulation of matter at the molecular scale, is already providing environmental benefits for buildings.

Although the market for nano-enhanced building materials in the U.S. was under $20 million in 2006, it’s expected to grow to $400 million by 2016. $4 billion a year is being pumped into nanotech R&D worldwide, resulting in a pipeline of materials and products that will transform the way future buildings are made.

Nano has the potential to greatly reduce emissions from buildings - which produce 43% of the world’s CO2 emissions - reduce construction waste, which accounts for 40% of landfill materials, while providing cleaner air and water inside buildings.

In the first wave, nanotech is making its way into insulation, coatings and solar PV. The next wave, currently in the development stage, will bring advances in lighting technology, air and water purification. In about ten years we’ll begin to see changes in structural components like concrete and steel, adhesives, and batteries.

We interviewed George Elvin, who recently published the fascinating report, “Nanotechnology for Green Building,” which identifies 130 startups and established companies offering or developing nanomaterials for green building. Elvin is director of the Green Technology Forum and Associate Professor at Ball State University.

Examples of green technology subject areas

Perhaps the most urgent issue for green technology, this includes the development of alternative fuels, new means of generating energy and energy efficiency.

Green building
Green building encompasses everything from the choice of building materials to where a building is located.

Environmentally preferred purchasing
This government innovation involves the search for products whose contents and methods of production have the smallest possible impact on the environment, and mandates that these be the preferred products for government purchasing.

Environmentally Preferred Purchasing
This government innovation involves the search for products whose contents and methods of production have the smallest possible impact on the environment, and mandates that these be the preferred products for government purchasing.

Green Chemistry
The invention, design and application of chemical products and processes to reduce or to eliminate the use and generation of hazardous substances.

Green Nanotechnology
Nanotechnology involves the manipulation of materials at the scale of the nanometer, one billionth of a meter. Some scientists believe that mastery of this subject is forthcoming that will transform the way that everything in the world is manufactured. “Green nanotechnology” is the application of green chemistry and green engineering principles to this field.

The Top 10 U.S. Cities with the Most Green Buildings
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Every decently sized company with a PR team can claim to be going green these days. But how do you separate those who simply hang out an Earth Flag once a year to those who make real commitments in their daily activities? One good way is by looking at their physical facilities, since commercial and industrial buildings in the U.S. are responsible for about 45% of the country's greenhouse gas emissions and 50% of energy use.

America's 4.8 million commercial buildings and 350,000 industrial facilities expend $107.9 billion and $94.4 billion a year on energy costs, according to the EPA's Energy Star program. Yet an estimated 30% of that cost – enormous as it is – is actually wasted due to inefficient technologies. What's more, according to Energy Star, if the energy efficiency of our commercial and industrial buildings was boosted by an attainable 10% across the board, that would result in reduction of greenhouse gases equivalent to taking 30 million vehicles off our roads (or about as many cars and trucks as are registered in Illinois, New York, Texas and Ohio combined).

How do you make sure a green building is really greener? One convenient way is third party certification. The gold standard has been the Leadership in Energy and Environmental Design (LEED) program from the U.S. Green Building Council. Another one increasingly gaining familiarity is the EPA's Energy Star label program, which was extended from appliances and electronics to whole structures fairly recently.

According to the EPA, the number of Energy Star-qualified buildings across the U.S. has soared by more than 130% from 2007. What does that really mean? Energy Star buildings use 35% less energy than average buildings and emit 35% less carbon dioxide into the atmosphere.

Of course, it is important to remember that energy use and emissions are not the only factors to consider when asking if a building is green. There are also issues of indoor air quality, water conservation, recycled content, habitat protection, access to transportation, support for bicycles and hybrid vehicles, and impact on local wildlife (no glass walls of death!). Still, energy use is a major consideration.

In 2008, more than 3,300 commercial buildings and manufacturing plants earned Energy Star. These structures saved more than $1.1 billion in energy costs and reduced more than 7 million metric tons of greenhouse gas emissions in 2008 -- equal to the emissions created in powering more than 1 million homes for a year. There are now more than 6,200 Energy Star-qualified buildings and plants throughout the U.S., which have saved $1.7 billion in energy costs and reduced more than 13 million metric tons in greenhouse gas emissions annually, equivalent to the emissions associated with the electricity use of more than 1.8 million homes a year.

The top ten city rankings based on the number of Energy Star-qualified buildings in 2008 are:

1) Los Angeles, CA
2) San Francisco, CA
3) Houston, TX
4) Washington D.C.
5) Dallas-Fort Worth, TX
6) Chicago, IL
7) Denver, CO
8) Minneapolis-St. Paul, MN
9) Atlanta, GA
10) Seattle, WA


Top 10 Green-Tech Breakthroughs of 2008

Wired Magazine has come up with a list of what it thinks were the top ten green-technology breakthroughs of last year. The list includes advances in solar power from companies such as BrightSource, Ausra, and Nanosolar; actual pilot projects involving Shai Agassi’s Better Place replaceable electric car battery idea; and a demonstration site for making cement from CO2 left over from power generation. Perhaps just as significant but less acknowledged (number four on Wired’s list) is the selection of Steven Chu, a Nobel-prize winning physicist (detailed autobiography here), to head the Department of Energy. While at Lawrence Berkley National Laboratory, Chu was focused on alternative-energy. In addition, he often speaks candidly about the dangers of climate change. Having such an advocate for clean technology in the White House is especially important given that the world economy has fallen into recession and the price of oil has dropped, if only for the short-term. When energy prices drop, investments in alternative or clean technology aren’t as attractive. In the absence of other incentives, development, research, and production of new technology will slow dramatically. There was an oil shock in the 1970’s that forced us to move to smaller, more efficient cars and opened the door to innovation. Yet we ended up with a return to cheap gas and a love affair with SUVs. Let’s hope Secretary Chu can help us avoid falling into the same pattern this time around.



The Top 10 Green-Tech Breakthroughs of 2008

By Alexis Madrigal EmailDecember 29, 2008 | 2:29:56 PMCategories: Chemistry, Clean Tech, Climate, Energy, Engineering, Environment, Geology, Science, Survival, Sustainability  

Green technology was hot in 2008. Barack Obama won the presidential election promising green jobs to Rust Belt workers. Investors poured $5 billion into the sector just through the first nine months of the year. And even Texas oilmen like T. Boone Pickens started pushing alternative energy as a replacement for fossil fuels like petroleum, coal and natural gas.

But there's trouble on the horizon. The economy is hovering somewhere between catatonic and hebephrenic, and funding for the big plans that green tech companies laid in 2008 might be a lot harder to come by in 2009. Recessions haven't always been the best times for environmentally friendly technologies as consumers and corporations cut discretionary spending on ethical premiums.

Still, green technology and its attendant infrastructure are probably the best bet to drag the American economy out of the doldrums. So, with the optimism endemic to the Silicon Valley region, we present you with the Top 10 Green Tech Breakthroughs of 2008, alternatively titled, The Great Green Hope.

Prototypesolarisland

10. THE ISLAND OF THE SOLAR

With money flowing like milk and honey in the land of solar technology, all sorts of schemers and dreamers came streaming into the area. One Swiss researcher, Thomas Hinderling, wants to build solar islands several miles across that he claims can produce hundreds of megawatts of relatively inexpensive power. Though most clean tech advocates question the workability of the scheme, earlier this year, Hinderling's company Centre Suisse d'Electronique et de Microtechnique received $5 million from the Ras al Khaimah emirate of the United Arab Emirates to start construction on a prototype facility, shown above, in that country. (Image: Centre Suisse d'Electronique et de Microtechnique)

01_nanotech

9. NEW MATERIALS CAGE CARBON

Carbon capture and sequestration has a seductively simple appeal: We generate carbon dioxide emissions by burning geology — coal and oil — so to fix the problem, we should simply capture it and inject it back into the ground.

It turns out, however, that it's not quite so simple. Aside from finding the right kind of empty spaces in the earth's crust and the risks that the CO2 might leak, the biggest problem with the scheme is finding a material that could selectively snatch the molecule out of the hot mess of gases going up the flues of fossil fuel plants.

That's where two classes of special cage-like molecules come into play, ZIFs and amines. This year, Omar Yaghi, a chemist at UCLA, announced a slough of new CO2-capturing ZIFs and Chris Jones, a chemical engineer at Georgia Tech, reported that he'd made a new amine that seems particularly well-suited to working under real-world condition. Both materials could eventually make capturing CO2 easier -- and therefore, more cost effective.

Perhaps better still, Yaghi's lab's technique also defined a new process for quickly creating new ZIFs with the properties that scientists — and coal-plant operators — want. Some of their crystals are shown in the image above. (Image: Omar Yaghi and Rahul Banerjee/UCLA)

8. GREEN TECH LEGISLATION GETS REAL

On the federal and state levels, several historic actions put the teeth into green tech bills passed over the last few years. A review committee of the EPA effectively froze coal plant construction, a boon to alternative energy (though earlier this month the EPA ignored the committee's ruling and it is unclear how the issue will be settled). In California, the state unveiled and approved its plan to regulate carbon dioxide emissions, which could be a model for a nationwide system. Combined with the green-energy tax credits in the $700-billion bailout bill, the government did more for green tech in 2008 than in whole decades in the past. 

7. THE CATALYST THAT COULD ENABLE SOLAR

In July, MIT chemist Daniel Nocera announced that he'd created a catalyst that could drop the cost of extracting the hydrogen and oxygen from water.

Combined with cheap photovoltaic solar panels (like Nanosolar's), the system could lead to inexpensive, simple systems that use water to store the energy from sunlight. In the process, the scientists may have cleared the major roadblock on the long road to fossil fuel independence: Reducing the on-again, off-again nature of many renewable power sources.

"You've made your house into a fuel station," Daniel Nocera, a chemistry professor at MIT told Wired.com. "I've gotten rid of all the goddamn grids."

The catalyst enables the electrolysis system to function efficiently at room temperature and at ordinary pressure. Like a reverse fuel cell, it splits water into oxygen and hydrogen. By recombining the molecules with a standard fuel cell, the O2 and H2 could then be used to generate energy on demand.

6. PICKENS PLAN PUSHES POWER PLAYS INTO AMERICAN MAINSTREAM

Texas oilman T. Boone Pickens might be a lot of things, but environmentalist he is not. That's why his support for a nationwide network of wind farms generated so much excitement. While his solution for transportation, natural gas vehicles, may not pan out, his Pickens Plan is the most visible alternative energy plan out there and it began to channel support from outside coastal cities for finding new sources of energy.

Of course, no one said Pickens is stupid. If his plan was adopted and major investments in transmission infrastructure were made, his wind energy investments would stand to benefit.

5. SOLAR THERMAL PLANTS RETURN TO THE DESERTS

When most people think of harnessing the sun's power, they imagine a solar photovoltatic panel, which directly converts light from the sun into electricity. But an older technology emerged as a leading city-scale power technology in 2008: solar thermal. Companies like Ausra, BrightSource, eSolar, Solel, and a host of others are using sunlight-reflecting mirrors to turn liquids into steam, which can drive a turbine in the same way that coal-fired power plants make electricity. 

Two companies, BrightSource and Ausra, debuted their pilot plants. They mark the first serious solar thermal experimentation in the United States since the 1980s. BrightSource's Israeli demo plant is shown above. (Image: BrightSource)

4. OBAMA PICKS A GREEN TECH EXPERT TO HEAD DOE

President-elect Barack Obama ran on the promise of green jobs and an economic stimulus package that would provide support for scientific innovation. Then, Obama picked Steven Chu, a Nobel-prize winning physicist, to head the Department of Energy. Chu had been focused on turning Lawrence Berkeley National Laboratory into an alternative-energy powerhouse. The green tech community rejoiced that one of their own would be in the White House.

That's because green tech is going to need some help. With the world economy falling into recession, the price of oil has dropped, even though there are serious concerns about the long-term oil supply. When energy prices drop, clean tech investments don't seem quite as attractive, and the renascent industry could be in trouble. It's happened before, after all.

Back in the '70s, geopolitical events sent the price of oil soaring, which, as it tends to, created a boom in green tech. But the early 1980s saw the worst recession since the Depression. Sound familiar? In the poor economic climate, focus and funds were shifted away from green tech. The last nail in the coffin was the election of Ronald Reagan, who immediately pulled off the solar panels Jimmy Carter had placed on the White House. The green tech industry collapsed.

History has given U.S. alternative energy research a second chance and environmental advocates hope that a different president will lead to a very different result. (Image: DOE)

3. SOLAR CELL PRODUCTION GETS BIG, GIGA(WATT)BIG

Every clean tech advocate's dream is a power-generating technology that could compete head-to-head with coal, the cheapest fossil fuel, on price alone. Nanosolar, one of a new generation of companies building solar panels out of cheap plastics, could be the first company to get there. Early this year, the company officially opened its one-gigawatt production facility, which is many times the size of most previous solar facilities.

Nanosolar, in other words, has found a process that can scale: it works as well in production as it does in the lab. That's the main reason that the company has picked up half-a-billion dollars in funding from investors like MDV's Erik Straser.

"[It's the] first time in industry a single tool with a 1GW throughput," Straser wrote in an e-mail. "It's a key part of how the company is achieving grid parity with coal."

2. PROJECT BETTER PLACE FINDS HOMES
Green technologies are dime a dozen, but a business model that could allow an entirely new, green infrastructure to be built is a rare thing.

Doing just that is the centerpiece of Sun Microsystems' SAP veteran Shai Agassi's vision for Project Better Place, a scheme that would distribute charging and swappable battery stations throughout smallish geographies like Israel, Hawaii and San Francisco. So far, there's very little steel in the ground, but in early December, the company's first charging location opened in Tel Aviv, Israel. Agassi's plan is one of several projects — like new biofuels rail terminals — that could create fundamentally new energy ecosystems.

Some of these systems, however, are actually throwbacks to earlier eras. As Peter Shulman, a historian of technology at Case Western Reserve University, likes to remind his students: in the early 20th century, before the Model T, one-third of all cars were electric. (Image: Joe Puglies/WIRED)                                                                          

1. CALERA'S GREEN CEMENT DEMO PLANT OPENS

Cement? With all the whiz bang technologies in green technology, cement seems like an odd pick for our top clean technology of the year. But here's the reason: making cement — and many other materials — takes a lot of heat and that heat comes from fossil fuels.

Calera's technology, like that of many green chemistry companies, works more like Jell-O setting. By employing catalysis instead of heat, it reduces the energy cost per ton of cement. And in this process, CO2 is an input, not an output. So, instead of producing a ton of carbon dioxide per ton of cement made — as is the case with old-school Portland cement — half a ton of carbon dioxide can be sequestered.

With more than 2.3 billion tons of cement produced each year, reversing the carbon-balance of the world's cement would be a solution that's the scale of the world's climate change problem.

 

 notebook

A netbook (a portmanteau of Internet and notebook) is a class of laptop computer designed for wireless communication and access to the Internet.[1]

Primarily designed for web browsing and e-mailing, netbooks rely heavily on the Internet for remote access to web-based applications"[2] and are targeted increasingly at cloud computing users who require a less powerful client computer.[3] Netbooks typically run either Linux or Windows XP operating systems[2] rather than more resource-intensive operating systems like Windows Vista.[4] The devices range in size from below 5 inches[5] to over 13,[6] typically weigh 2 to 3 pounds (~1 kg) and are often significantly cheaper than general purpose laptops.[2]


y late 2008, netbooks had begun to take market share away from laptops.[10] It is estimated that almost thirty times more netbooks were sold in 2008 (11.4 million, 70% of which were in Europe[11]) than in 2007 (400,000).[12] For 2009 sales are expected to jump to 35 million, rising to an estimated 139 million in 2013.[13] This trend is reinforced by the rise of web-based applications as well as mobile networking and, according to Wired Magazine, netbooks are evolving into "super-portable laptops for professionals".[14]


In vitro fertilisation

 
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In vitro fertilisation (IVF) is a process by which egg cells are fertilised by sperm outside of the womb, in vitro. IVF is a major treatment in infertility when other methods of assisted reproductive technology have failed. The process involves hormonally controlling the ovulatory process, removing ova (eggs) from the woman's ovaries and letting sperm fertilise them in a fluid medium. The fertilised egg (zygote) is then transferred to the patient's uterus with the intent to establish a successful pregnancy. The first test tube baby, Louise Brown, was born in 1978.

Oocyte with surrounding granulosa cells
"Naked" Egg

The term in vitro, from the Latin root meaning within the glass, is used, because early biological experiments involving cultivation of tissues outside the living organism from which they came, were carried out in glass containers such as beakers, test tubes, or petri dishes. Today, the term in vitro is used to refer to any biological procedure that is performed outside the organism it would normally be occurring in, to distinguish it from an in vivo procedure, where the tissue remains inside the living organism within which it is normally found. A colloquial term for babies conceived as the result of IVF, test tube babies, refers to the tube-shaped containers of glass or plastic resin, called test tubes, that are commonly used in chemistry labs and biology labs. However, in vitro fertilisation is usually performed in the shallower containers called Petri dishes. (Petri-dishes may also be made of plastic resins.) However, the IVF method of Autologous Endometrial Coculture is actually performed on organic material, but is yet called in vitro. This is used when parents are having infertility problems or they want to have multiple births.Initially IVF was developed to overcome infertility due to problems of the fallopian tube, but it turned out that it was successful in many other infertility situations as well. The introduction of intracytoplasmic sperm injection (ICSI) addresses the problem of male infertility to a large extent.

For IVF to be successful it may be easier to say that it requires healthy ova, sperm that can fertilise, and a uterus that can maintain a pregnancy. Due to the costs of the procedure, IVF is generally attempted only after less expensive options have failed.

This means that IVF can be used for females who have already gone through menopause. The donated oocyte can be fertilised in a crucible. If the fertilisation is successful, the zygote will be transferred into the uterus, within which it will develop into an embryo.

Method

[edit] Ovarian stimulation

Treatment cycles are typically started on the third day of menstruation and consist of a regimen of fertility medications to stimulate the development of multiple follicles of the ovaries. In most patients injectable gonadotropins (usually FSH analogues) are used under close monitoring. Such monitoring frequently checks the estradiol level and, by means of gynecologic ultrasonography, follicular growth. Typically approximately 10 days of injections will be necessary. Spontanenous ovulation during the cycle is typically prevented by the use of GnRH agonists or GnRH antagonists, which block the natural surge of luteinising hormone (LH).

[edit] Egg retrieval

When follicular maturation is judged to be adequate, human chorionic gonadotropin (β-hCG) is given. This agent, which acts as an analogue of luteinising hormone, would cause ovulation about 42 hours after injection, but a retrieval procedure takes place just prior to that, in order to recover the egg cells from the ovary. The eggs are retrieved from the patient using a transvaginal technique involving an ultrasound-guided needle piercing the vaginal wall to reach the ovaries. Through this needle follicles can be aspirated, and the follicular fluid is handed to the IVF laboratory to identify ova. It is common to remove between ten and thirty eggs. The retrieval procedure takes about 20 minutes and is usually done under conscious sedation or general anesthesia.

[edit] Fertilisation

In the laboratory, the identified eggs are stripped of surrounding cells and prepared for fertilisation. In the meantime, semen is prepared for fertilisation by removing inactive cells and seminal fluid. If semen is being provided by a sperm donor, it will usually have been prepared for treatment before being frozen and quarantined, and it will be thawed ready for use. The sperm and the egg are incubated together (at a ratio of about 75,000:1) in the culture media for about 18 hours. In most cases, the egg will be fertilised by that time and the fertilised egg will show two pronuclei. In certain situations, such as low sperm count or motility, a single sperm may be injected directly into the egg using intracytoplasmic sperm injection (ICSI). The fertilised egg is passed to a special growth medium and left for about 48 hours until the egg has reached the 6-8 cell stage.

[edit] Selection

Laboratories have developed grading methods to judge oocyte and embryo quality. Typically, embryos that have reached the 6-8 cell stage are transferred three days after retrieval. In many American and Australian programmes[citation needed], however, embryos are placed into an extended culture system with a transfer done at the blastocyst stage at around five days after retrieval, especially if many good-quality embryos are still available on day 3. Blastocyst stage transfers have been shown to result in higher pregnancy rates.[1] In Europe, transfers after 2 days are common.

[edit] Embryo transfer

Embryos are graded by the embryologist based on the number of cells, evenness of growth and degree of fragmentation. The number to be transferred depends on the number available, the age of the woman and other health and diagnostic factors. In countries such as the UK, Australia and New Zealand, a maximum of two embryos are transferred except in unusual circumstances. In the UK and according to HFEA regulations, a woman over 40 may have up to three embryos transferred, whereas in the USA, younger women may have many embryos transferred based on individual fertility diagnosis. Most clinics and country regulatory bodies seek to minimise the risk of pregnancies carrying multiples. The embryos judged to be the "best" are transferred to the patient's uterus through a thin, plastic catheter, which goes through her vagina and cervix. Several embryos may be passed into the uterus to improve chances of implantation and pregnancy.

 Pregnancy rates

Pregnancy rate is the success rate for pregnancy. For IVF, it is the percentage of all attempts that lead to pregnancy, with attempts generally referring to menstrual cycles where eggs are retrieved and fertilised in vitro.

With enhanced technology, the pregnancy rates are substantially better today than a couple of years ago. In 2006, Canadian clinics reported an average pregnancy rate of 35%.[2]

[edit] Effect of stress

According to a 2005 Swedish study published in the Oxford Journal Human Reproduction, 166 women were monitored starting one month before their IVF cycles and the results showed no significant correlation between psychological stress and their IVF outcomes. The study concluded with the recommendation to clinics that it might be possible to reduce the stress experienced by IVF patients during the treatment procedure by informing them of those findings. While psychological stress experienced during a cycle might not influence an IVF outcome, it is possible that the experience of IVF can result in stress that leads to depression. The financial consequences alone of IVF can influence anxiety and become overwhelming. However, for many couples, the alternative is infertility, and the experience of infertility itself can also cause extreme stress and depression.

Live birth rate

Live birth rate is the percentage of all IVF cycles that lead to live birth, and is the pregnancy rate adjusted for miscarriage.

In 2006, Canadian clinics reported a live birth rate of 27%.[2] In 2007 Australian clinics recorded that the live birth rate was 84%, [3]

Complications

The major complication of IVF is the risk of multiple births. This is directly related to the practice of transferring multiple embryos at embryo transfer. Multiple births are related to increased risk of pregnancy loss, obstetrical complications, prematurity, and neonatal morbidity with the potential for long term damage. Strict limits on the number of embryos that may be transferred have been enacted in some countries (e.g., England) to reduce the risk of high-order multiples (triplets or more), but are not universally followed or accepted. Spontaneous splitting of embryos in the womb after transfer can occur, but this is rare and would lead to identical twins. A double blind, randomised study followed IVF pregnancies that resulted in 73 infants (33 boys and 40 girls) and reported that 8.7% of singleton infants and 54.2% of twins had a birth weight of < 2500 g.[4] However recent evidence suggest that singleton offspring after IVF is at higher risk for lower birth weight for unknown reasons.

Another risk of ovarian stimulation is the development of ovarian hyperstimulation syndrome.

If the underlying infertility is related to abnormalities in spermatogenesis, it is plausible, but too early to examine that male offspring is at higher risk for sperm abnormalities.

[edit] Birth defects

The issue of birth defects has been a controversial topic in IVF. Many studies do not show a significant increase after use of IVF, and some studies suggest higher rates for ICSI, whereas others do not support this finding.[5] In 2008, an analysis of the data of the National Birth Defects Study in the US found that certain birth defects were significantly more common in infants conceived with IVF, notably septal heart defects, cleft lip with or without cleft palate, esophageal atresia, and anorectal atresia; the mechanism of causality is unclear.[6]

Japan's government prohibited the use of in vitro fertilisation procedures for couples in which both partners are infected with HIV. Despite the fact that the ethics committees previously allowed the Ogikubo Hospital, located in Tokyo, to use in vitro fertilisation for couples with HIV, the Health, Labour and Welfare Ministry of Japan decided to block the practice. Hideji Hanabusa, the vice president of the Ogikubo Hospital, states that together with his colleagues, he managed to develop a method through which scientists are able to remove the AIDS virus from sperm.[7

Cryopreservation

[edit] Embryo cryopreservation

The first pregnancy derived from a frozen human embryo was reported by Allan Trounson & Linda Mohr in 1983 (although the pregnancy aborted spontaneously at about 20 weeks of gestation); the first term pregnancies derived from frozen human embryos were reported by Zeilmaker et al. and the first human baby hatched via a rate frozen freezing process was born in 1984. Since then and up to 2008 it is estimated that between 350,000 and half a million IVF babies have been born from embryos controlled rate frozen and then stored in liquid nitrogen; additionally a few hundred births have been born from vitrified oocytes but firm figures are hard to come by.

On the safety of embryo cryopreservation, a 2008 study reported at the European Society for Human Reproduction and Embryology discovered that children born from frozen embryos did “better and had a higher birth weight” than children born from a fresh transfer. The study was conducted out of Copenhagen and evaluated babies born during the years 1995–2006. 1267 children born after Frozen Embryo Replacement (FER), via controlled-rate freezers and storage in liquid nitrogen, were studied and categorised into three groups. 878 of them were born using frozen embryos that were created using standard in vitro fertilisation in which the sperm were placed into a dish close to the egg but had to penetrate the egg on their own. 310 children were born with frozen embryos created using ICSI in which a single sperm was injected into a single egg, and 79 were born where the method of creation of the embryos was not known.

17,857 babies born after a normal IVF/ICSI with fresh embryos were also studied and used as a control group or reference group. Data on all of the children’s outcomes were taken regarding birth defects, birth weights, and length of pregnancy. The results of the study showed that the children who came from frozen embryos had higher birth weights, gave longer pregnancies and produced fewer “pre-term” births. There was no difference in the rate of birth defects whether the children came from frozen embryos or fresh embryos. In the FER group, the birth defect rate was 7.7% compared to the fresh transfer group which was slightly higher at 8.8%. The scientists also found that the risk for multiple pregnancies was increased in the fresh embryo transfers.

Around 11.7% of the ICSI and 14.2% of the IVF frozen cases were multiple pregnancies. In the case of fresh embryos, 24.8% of the ICSI and 27.3% of the IVF were multiple pregnancies. It should also be noted that maternal age was significantly higher in the FER group. This is significant since based on age one would have expected a higher rate of problems and birth defects. The study adds to the body of knowledge suggesting that traditional embryo freezing is a safe procedure. It was unclear however why the frozen embryo children did better than their fresh embryo counterparts

If multiple embryos are generated, patients may choose to freeze embryos that are not transferred. Those embryos are slow frozen and then placed in liquid nitrogen and can be preserved for a long time. There are currently 500,000 frozen embryos in the United States.[8] The advantage is that patients who fail to conceive may become pregnant using such embryos without having to go through a full IVF cycle. Or, if pregnancy occurred, they could return later for another pregnancy. Spare embryos resulting from fertility treatments may be donated to another woman or couple, and embryos may be created, frozen and stored specifically for transfer and donation by using donor eggs and sperm.

[edit] Oocyte cryopreservation

Cryopreservation of unfertilised mature oocytes has been successfully accomplished, e.g. in women who are likely to lose their ovarian reserve due to undergoing chemotherapy.[9] It should be note that the rate of thaw leading to successful pregnancies is still very low.

[edit] Ovarian tissue cryopreservation

Cryopreservation of ovarian tissue is of interest to women who want to preserve their reproductive function beyond the natural limit, or whose reproductive potential is threatened by cancer therapy. Research on this issue is promising.

 Variations

There are several variations or improvements of IVF:

PGD
PGD (Preimplantation Genetic Diagnosis) can be performed on embryos before the embryo transfer. A similar but more general test has been developed called Preimplantation Genetic Haplotyping (PGH).
ICSI
ICSI (Intracytoplasmic Sperm Injection) is a more recent development associated with IVF that allows the sperm to be injected directly into the egg. This is used when sperm have difficulty penetrating the egg, and in these cases the partner's or a donor's sperm may be used. ICSI is also used when sperm numbers are very low. ICSI results in success rates equal to those of IVF fertilisation.
ZIFT
In the process of ZIFT (Zygote Intrafallopian Transfer), eggs are removed from the woman, fertilised, and then placed in the woman's fallopian tubes rather than the uterus.
GIFT
In the GIFT (Gamete Intra-Fallopian Transfer) process, eggs are removed from the woman and placed in one of the fallopian tubes, along with the man's sperm. This allows fertilisation to take place inside the woman's body. Therefore, this variation is actually an in vivo fertilisation, not an in vitro fertilisation.
 
 Embryo & Oocyte Donation

The first transfer of an embryo from one human to another resulting in pregnancy was reported in July 1983 and subsequently led to the announcement of the first human birth February 3, 1984.[10] It was accomplished by in vivo fertilisation, a process that was derived from animal husbandry. This procedure was performed at the Harbor UCLA Medical Center [11] under the direction of Dr.John Buster and the University of California at Los Angeles School of Medicine.

In the procedure, an embryo that was just beginning to develop was transferred from one woman in whom it had been conceived by artificial insemination to another woman who gave birth to the infant 38 weeks later. The sperm used in the artificial insemination came from the husband of the woman who bore the baby.[12][13]

Donor embryo transfer has given women a mechanism to become pregnant and give birth to a child that will contain their husband’s genetic makeup. Although donor embryo transfer as practiced today has evolved from the original non-surgical method, it now accounts for approximately 5% of in vitro fertilization recorded births.

Prior to this, women who were infertile, had adoption as the only path to parenthood. This set the stage to allow open and candid discussion of embryo donation and transfer. This breakthrough has given way to the donation of human embryos as a common practice similar to other donations such as blood and major organ donations. At the time of this announcement the event was captured by major news carriers and fueled healthy debate and discussion on this practice which impacted the future of reproductive medicine by creating a platform for further advancements in woman's health.

This work established the technical foundation and legal-ethical framework surrounding the clinical use of human oocyte and embryo donation, now a mainstream clinical practice that has evolved over the past 25 years.[12][14] Since the initial birth announcement in 1984, well over 47,000 live births resulting from donor embryo transfer have been and continue to be recorded by the Centers for Disease Control(CDC)[15] in the United States.[16][17]

[edit] Acupuncture

An increasing number of fertility specialists and centers offer acupuncture as a part of their IVF protocol. Limited but supportive evidence from clinical trials and case series suggests that acupuncture may improve the success rate of IVF and the quality of life of patients undergoing IVF and that it is a safe adjunct therapy.[18] A systematic review and meta-analysis published in the British Medical Journal found that complementing the embryo transfer process with acupuncture was associated with significant and clinically relevant improvements in clinical pregnancy (where the expected number of patients needed to be treated to produce 1 additional pregnancy was 10), ongoing pregnancy (NNT 9), and live birth (NNT 9).[19]



Suleman octuplets

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The Suleman octuplets are six male and two female children conceived via in-vitro fertilization (IVF) and simultaneously born to 33-year-old Nadya Suleman on January 26, 2009, in Bellflower, California. They are only the second full set of octuplets to be born alive in the United States and, one week after their birth, surpassed the previous worldwide survivial rate for a complete set of octuplets set by the Chukwu octuplets in 1998. The circumstances of their high order multiple birth has led to controversy in the field of assisted reproductive technology as well as an investigation by the Medical Board of California of the fertility specialist involved.[1]

 

[edit] Names

The babies' names, gender and birth weight in birth order are:[2][3][4]

  • Noah Angel Solomon - male; 2 lbs 8 oz
  • Maliyah Angel Solomon - female; 2 lbs 2 oz
  • Isaiah Angel Solomon - male; 3 lbs 1 oz
  • Nariyah Angel Solomon - female; 2 lbs 3 oz
  • Makai Angel Solomon - male; 1 lbs 12 oz
  • Josiah Angel Solomon - male; 2 lbs 9 oz
  • Jeremiah Angel Solomon - male; 1 lb 13 oz
  • Jonah Angel Solomon - male; 2 lbs 7 oz

Although mother Nadya Suleman states there are two sets of identical (monozygotic) twins among the octuplets due to division of two of the claimed six implanted embryos,[5] she has not identified which of the octuplets are sets of identical twins.

[edit] Background

[edit] Conception

The octuplets were conceived by in-vitro fertilization (IVF) conducted by Doctor Michael Kamrava. Nadya Suleman had six embryos remaining from previous IVF treatments transferred, despite being informed that for a woman her age the recommended guideline limit was three.[1] A part of her reasoning for attempting another pregnancy was so that the frozen embryos wouldn't be destroyed.[citation needed] Six embryos were transferred and two embryos split into twins, resulting in eight babies. The mother's health and gestational status were followed from her first trimester. Five fetuses were evident after one month and Suleman was offered the option of selective reduction, which she declined.[6][7][8][9][10][11][12][13]

[edit] Birth

The delivery, via a scheduled Caesarean section, involved 46 medical personnel, and was practiced twice beforehand at the Kaiser Permanente hospital in Bellflower, California. Doctors anticipated seven babies, so the eighth came as a surprise. Born over the course of five minutes, all eight babies were immediately reported in stable condition, though two required intubation and a ventilator, and another required extra oxygen.[14]

[edit] Post delivery

Two days after birth, five of the eight infants received their first tube-feeding of donated breast milk. Josiah rejected his first tube-feeding and was returned to intravenous feeding, his stomach as yet unable to absorb breast milk. At that time, three of the other infants had been fed intravenously since birth, and were yet to receive their first tube-feeding.[15][16][17]

Six days after birth, all eight babies were breathing without assistance, and were being fed donated breast milk, as well as intravenous nutritional supplements. A hospital spokesman said the octuplets were expected to remain in the hospital for several more weeks.[18]

One week after birth, the Suleman octuplets became the longest-living octuplets in United States history, as the smallest of the Chukwu octuplets born in Houston in 1998 died seven days after birth.[19][20]

The hospital where the octuplets are expected to spend seven to twelve weeks has requested reimbursement from Medi-Cal, the state's Medicaid program, for care of the premature babies.[21]

[edit] Family

[edit] Mother

Nadya Suleman was born on October 12, 1975 in Fullerton, California and was raised in La Puente, Hacienda Heights and Rowland Heights, all cities in the San Gabriel Valley of Los Angeles County.[22][23][24] She is the only child of Edward and Angela Doud, who married in Las Vegas in 1974, and divorced in 1999.[25]

Ten days after the birth of her octuplets, Suleman was released from the hospital. In her February 5, 2009 interview, Suleman stated that she holds each of the octuplets for 45 minutes a day, holding the smallest (born at 1 lb., 12 oz.) the longest.[26][27]


[edit] Biological father

Suleman's mother stated that a single sperm donor named David Solomon[28] was used to produce the octuplets as well as her daughter's previous six children.[29][11] Nadya stated that she dated David once, but realized after that she only wanted him to father her children and not pursue a relationship with him.[30] Other sources claim that Nadya made up the name David Solomon in order not to identify the actual sperm donor.[31]

On the February 23, 2009 edition of ABC's Good Morning America, a man named Denis Beaudoin claimed to be the biological father of Suleman's children. He stated they dated from 1997 to 1999 and Suleman asked him if he would donate the sperm. Beaudoin is requesting a paternity test be performed to verify his claim. Suleman has since denied that he was the donor.[32][33][34]

[edit] Siblings

The octuplets have six older siblings age 2 to 7 (born between 2001 and 2006) who were also conceived via IVF with the same sperm donor according to statements made by mother Nadya Suleman.[35][28][36] They are:

  • 7-year-old Elijah Makai Solomon (boy)
  • 6-year-old Amerah Yasmeen Solomon (girl)
  • 5-year-old Joshua Jacob Solomon (boy)
  • 3-year-old Aiden Solomon (boy)
  • 2-year-old Calyssa Arielle Solomon (girl, fraternal twin)
  • 2-year-old Caleb Kai Solomon (boy, fraternal twin)

[edit] Grandparents

The octuplets' maternal grandfather, 67-year-old Edward Doud Suleman,[37] identifying himself as a former Iraqi military man, says he is returning to his native Iraq as a translator and driver, in order to financially support his daughter and her children.[38][39] Their grandmother, 69-year-old Angela Victoria Suleman, a retired teacher, has helped to look after the first six children. She has indicated that she is overwhelmed looking after them, and has been critical of her daughter in her recent public statements. For example, she has stated that her daughter has not contributed toward housing or food costs.[40][40][41][40][42][43][44][45]

[edit] Controversy

The implantation of six embryos in a woman under 35 years of age who already had children raised controversies and led to calls for legislation to limit the number of simultaneous embryo transfers.[citation needed] Additional public controversy arose when it was revealed that Suleman was unmarried, unemployed, and on public assistance.[citation needed]

News of the octuplets caused an international media frenzy.[46] Most public reply has been negative, including some death threats, which police are investigating.[47][48] There has been much public discussion about Nadya Suleman's decision to have the octuplets,[49][50] including a minor protest outside the Suleman home. However, Suleman currently lives elsewhere.[51] Many expressed concern that Suleman's decision for more children would burden taxpayers via public support.[52]

The Medical Board of California announced on February 6, 2009, that it was investigating Michael Kamrava, the physician who transferred the embryos, in an attempt to substantiate if there was a violation of the standard of care. The American Society for Reproductive Medicine has expressed interest in assisting the Board in its investigation.[53][54][55] The doctor also provided fertility treatment to a 49-year-old woman who is uninsured, 5 months pregnant with quadruplets, and hospitalized at Los Angeles County-USC Medical Center. At least seven embryos were used.[56][57]

[edit] See also


Department of Science and Technology (Philippines)

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Department of Science and Technology
Kagawaran ng Agham at Teknolohiya
Department of Science and Technology
Agency overview
Formed January 30, 1987
Headquarters DOST Bldg. Gen. Santos Avenue, Bicutan, Taguig
Annual budget P3.511 billion (2007)[1]
Agency executive Estrella F. Alabastro, Secretary of Science and Technology
Child agencies Food and Nutrition Research Institute (FNRI)
 
Philippine Nuclear Research Institute (PNRI)
 
Philippine Atmospheric, Geophysical and Astronomical Services Administration (PAGASA)
 
Philippine Institute of Volcanology and Seismology (PHIVOLCS)
Website
http://www.dost.gov.ph/

The Philippines' Department of Science and Technology (Filipino: Kagawaran ng Agham at Teknolohiya), abbreviated as the DOST, is the executive department of the Philippine Government responsible for the coordination of science and technology-related projects in the Philippines and to formulate policies and projects in the fields of science and technology in support of national development.

Contents

[hide]

[edit] History

The DOST was formed as the National Science Development Board in 1958, during the administration of Carlos P. Garcia. It was originally mandated to survey the state of science and technology development in the Philippines at the time. By 1982, during the administration of Ferdinand Marcos, it became the National Science and Technology Authority, or NSTA.

In 1987, when Corazon Aquino rose to power and in a shake-up of the executive departments, the NSTA was elevated to cabinet-level status to become the present-day DOST to meet the demands of the burgeoning fields of science and technology and increased calls from various sectors of Philippine society for state intervention in the fields of science and technology for the sake of national development.

[edit] Attached Agencies

[edit] About the Department of Science and Technology Logo

The logo of the Department of Science and Technology (DOST) consists essentially of four circles joined together side by side to form a square. The circles symbolize unit particles, the building blocks of nature which are the subject and substance of science and technology.

The circle design gives an illusion of movement signifying progress through Science and Technology.

The space in the center of the joined circles forms a four-pointed star symbolic of scientific creativity.

The logo' s three-color scheme represents the unknown(black), truth and enlightenment (white) and progress (blue).

The logo's four circles represent the four guiding principles in our S&T development: EXCELLENCE, RELEVANCE, COOPERATION and COST-EFFECTIVENES

DOST agency eyes more commercially viable RP patents

07/31/07

Posted under Patents

By Alex Villafania
INQUIRER.net

AS it celebrates its 20th anniversary, the Department of Science and Technology–Philippine Council for Advanced Science and Technology (DOST-PCASTRD) is setting its sights on strengthening the patent capabilities of the local scientific and engineering communities.

So far, the Philippines has produced a few patented technologies based from DOST-funded researches but the PCASTRD is looking to encourage more scientists to file patents as well as market these technologies to potential investors or business partners for use in different industries.

PCASTRD showcased seven supported projects, including a titanium nitride material coating process applicable for almost all large-scale industries, such as aeronautics and automobile manufacturing. This project was conducted by University of the Philippines Diliman professor Henry Ramos who was just awarded a patent from Taiwan last March and is in the process of acquiring patents in Singapore, Malaysia, the US and Europe.

A more recently approved patent was also an image-processing project from UP Diliman that involves combining an industrial-grade optical beam-induced imaging with confocal reflectance microscopy. Developed by UP Diliman researchers Cesar Saloma, Vincent Daria and Jelda Miranda, their project, whose patent was approved in the US on June 26, is aimed largely at the semiconductor industry and is useful for failure analysis in electronics components.

A third patented Filipino technology was from engineer Hilary De Leon who created a flight data recorder with wireless data retrieval. In simpler terms, it could enhance the way information is recorded and distributed in an aircraft and can be incorporated in current “black boxes” or flight recording modules.

During a press conference, PCASTRD Executive Director Reynaldo Ebora said the agency has been working with academic institutions that have strong research and development laboratories in an effort to get scientists to file patents.



Five Sectoral Planning Councils of DOST(Brief Function and Description)


DOST has five sectoral planning councils responsible for: formulating policies, plans, programs, projects and strategies for S&T development; for programming and allocating funds; for monitoring of research and development projects; and for generating external funds.

 

Philippine Council for Aquatic and Marine Research and Development (PCAMRD)

The PCAMRD is the sectoral council of the Department Of Science and Technology (DOST) tasked in the formulation of strategies, policies, plans, programs and projects for science and technology development; Programming and allocation of the government's internal and external funds for Research and Development; Monitoring and Evaluation of Research Development projects; and Generation of external funds.

 

Philippine Council for Agriculture, Forestry and Natural Resources Research and Development (PCARRD)

PCARRD is one of the five sectoral councils of the Department of Science and Technology (DOST). It serves as the main arm of DOST in planning, evaluating, monitoring, and coordinating the national research and development (R&D) programs in agriculture, forestry, environment, and natural resources sectors.

 

Philippine Council for Health Research and Development (PCHRD)

PCHRD is one of the five sectoral councils of the Department of Science and Technology (DOST). The lead council that creates and sustains an enabling environment for health research in the country.

 

Philippine Council for Industry and Energy Research and Development (PCIERD)

The PCIERD is one of the sectoral planning councils of the Department of Science and Technology (DOST). It is mandated to serve as the central agency in the planning, monitoring and promotion of scientific and technological research for applications in the industry, energy, utilities and infrastructure sectors.

 

Philippine Council for Advanced and Science Technology Research and Development (PCASTRD)

PCASTRD is one of the five sectoral councils of the Department of Science and Technology (DOST) tasked to develop, integrate and coordinate the national research systems for advanced science and technology (S&T) and related fields.

 

 Who is the Secretary of the Department of Science and Technology

 1. Strella Alabastro

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